Aldosterone and angiotensin II induce protein aggregation in renal proximal tubules

Muhammad U. Cheema, Ebbe T. Poulsen, Jan J. Enghild, Ewout Hoorn, Robert A. Fenton and Jeppe Praetorius

PHYSIOLOGICAL REPORTS Volume 1, Issue 4, September 2013 Article first published online : 10 SEP 2013, DOI: 10.1002/phy2.64

Quantitative apical membrane proteomics reveals vasopressin-induced actin dynamics in collecting duct cells.

Loo CS, Chen CW, Wang PJ, Chen PY, Lin SY, Khoo KH, Fenton RA, Knepper MA, Yu MJ.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17119-24. doi: 10.1073/pnas.1309219110. Epub 2013 Oct 1.

K+-induced natriuresis is preserved during Na+ depletion and accompanied by inhibition of the Na+-Cl- cotransporter.

van der Lubbe N, Moes AD, Rosenbaek LL, Schoep S, Meima ME, Danser AH, Fenton RA, Zietse R, Hoorn EJ.

Am J Physiol Renal Physiol. 2013 Oct;305(8):F1177-88. doi: 10.1152/ajprenal.00201.2013. Epub 2013 Aug 28.

New insights into regulated aquaporin-2 function.

Fenton RA, Pedersen CN, Moeller HB.

Curr Opin Nephrol Hypertens. 2013 Sep;22(5):551-8. doi: 10.1097/MNH.0b013e328364000d.

Expression and function of the lipocalin-2 (24p3/NGAL) receptor in rodent and human intestinal epithelia.

Langelueddecke C, Roussa E, Fenton RA, Thévenod F.

PLoS One. 2013 Aug 5;8(8):e71586. doi: 10.1371/journal.pone.0071586. Print 2013.

Phosphorylation of rat aquaporin-4 at Ser₁₁₁ is not required for channel gating.

Assentoft M, Kaptan S, Fenton RA, Hua SZ, de Groot BL, Macaulay N.

Glia. 2013 Apr 25. doi: 10.1002/glia.22498. [Epub ahead of print]

Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles.

Ballarín-González B, Dagnaes-Hansen F, Fenton RA, Gao S, Hein S, Dong M, Kjems J, Howard KA.

Mol Ther Nucleic Acids. 2013 Mar 5;2:e76. doi: 10.1038/mtna.2013.2.

Nephrogenic diabetes insipidus: essential insights into the molecular background and potential therapies for treatment.

Moeller HB, Rittig S, Fenton RA.

Endocr Rev. 2013 Apr;34(2):278-301. doi: 10.1210/er.2012-1044. Epub 2013 Jan 29.

Genetic ablation of aquaporin-2 in the mouse connecting tubules results in defective renal water handling.

Kortenoeven ML, Pedersen NB, Miller RL, Rojek A, Fenton RA.

J Physiol. 2013 Apr 15;591(Pt 8):2205-19. doi: 10.1113/jphysiol.2012.250852. Epub 2013 Jan 28.

Is there a role for PGE2 in urinary concentration?

Olesen ET, Fenton RA.

J Am Soc Nephrol. 2013 Feb;24(2):169-78. doi: 10.1681/ASN.2012020217. Epub 2012 Nov 15. 

Adenylyl cyclase 6 enhances NKCC2 expression and mediates vasopressin-induced phosphorylation of NKCC2 and NCC.

Rieg T, Tang T, Uchida S, Hammond HK, Fenton RA, Vallon V.

Am J Pathol. 2013 Jan;182(1):96-106. doi: 10.1016/j.ajpath.2012.09.014. Epub 2012 Nov 1.

Effects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties.

Lee DH, Maunsbach AB, Riquier-Brison AD, Nguyen MT, Fenton RA, Bachmann S, Yu AS, McDonough AA.

Am J Physiol Cell Physiol. 2013 Jan 15;304(2):C147-63. doi: 10.1152/ajpcell.00287.2012. Epub 2012 Oct 31.