To fulfill our research goals, InterPrET consists of a diverse group of researchers with the complete repertoire of multidisciplinary skills required for this research initiative.
The majority of center activities are at AU, thus there is direct interaction between participants. The center leader is Prof. Robert Fenton. A center committee has the overall responsibilities for scientific activities, budget, recruitments, coordinating researcher exchange and communication with university management.
Exchange programs and international networks ensure multidisciplinary training and vital international research experience (see International collaborations).
Center committee includes:
- Prof. Robert Fenton. Internationally recognized and respected investigator in epithelial membrane protein research. Skills include several of the cell/molecular biological and biochemical methodologies, advanced microscopy techniques and proteomics/bioinformatics analysis required for the research program.
- Prof. Jeppe Praetorius. Significant investigator in the field of epithelial transport and expert in state-of-the-art imaging techniques. Expertise in membrane protein tracking on the surface of living cells, membrane protein mapping, changes in polarization of membrane protein insertion, and assessment of membrane transporter function in intact cells. Laboratory equipment for live cell imaging of protein interactions and recently set up BRET analysis with applicant to study stoichiometry of protein complexes.
- Prof. Jan. J. Enghild. Extensive experience in protein structure and function, mass spectrometry and proteomics, protein misfolding diseases, proteases and proteases inhibitors, extracellelular matrix homeostasis, post-translational modifications, protein bio-molecules at surfaces, biocompatibility. Laboratory facilities for various proteomics techniques, including various mass spectrometers.
- Prof. Søren K. Moestrup. Expert in receptor-biology and protein interactions in a medical perspective. Laboratory facilities for advanced studies on intracellular membrane protein and receptor-ligand trafficking (e.g. live-imaging confocal microscopy) and molecular binding measurements (e.g. Biacore).
- Dr. Trairak Pisitkun. Skilled in proteomics and associated techniques to study cell biology and membrane proteins. Substantial programming skills in Java and has developed a number of computational tools for high-throughput data processing, bioinformatics, and analysis of protein networks. Creator of various online-databases and web applications for sharing of mass spectrometry data.
- Prof. Carsten Wiuf. Extensive expertise in mathematical and statistical modeling in bioscience, including mathematical genetics, statistics in microarray analysis and network dynamics. In recent years has been interested in structural aspects of proteins and protein dynamics. This includes modeling of large-scale protein-protein interaction networks and inference on their topological and evolutionary features, modeling of protein structure and dynamical modeling of enzymatic networks.